Publications
Research papers
Conference papers
Book Chapters
- Spatiotemporal transcriptome of the human brain
Hyo Jung Kang*, Yuka Imamura Kawasawa*, Feng Cheng*, Ying Zhu*, Xuming Xu, Mingfeng Li*, André M. M. Sousa, Mihovil Pletikos, Kyle A. Meyer, Goran Sedmak, Tobias Guennel, Yurae Shin, Matthew B. Johnson, Željka Krsnik, Simone Mayer, Sofia Fertuzinhos, Sheila Umlauf, Steven N. Lisgo, Alexander Vortmeyer, Daniel R. Weinberger, Shrikant Mane, Thomas M. Hyde, Anita Huttner, Mark Reimers, Joel E. Kleinman and Nenad Šestan
Nature 2011 478, 483–489
* Equal Contribution - In vitro transcriptomic prediction of hepatotoxicity for large drug screening
Feng Cheng, Dan Theodorescu Ira G. Schulman, and Jae K. Lee
Journal of Theoretical Biology 2011, 290C, 27-36 - Blood MicroRNAs: Novel ‘Omics’ Biomarkers for Ovarian Cancer Early Detection
Feng Cheng
Journal of Proteomics Bioinformatics 2012 5: xx-xxi - Genome-Wide Association Studies on Attention Deficit Hyperactivity Disorder
Kathryn Ashmore and Feng Cheng
Clin Exp Pharmacol 2013, 3:1 - Exploring the mysteries of traditional Chinese medicine systematically by expression microarrays
Feng Cheng
Drug Development Research 2012 73: 499–503 - Applications of Artificial Neural Network Modeling in Drug Discovery
Feng Cheng and Vijaykumar Sutariya
Clin Exp Pharmacol 2012 2:e113 - Beclin 1 and nuclear factor-κBp65 are upregulated in hepatocellular carcinoma
Kai‑Fu Kang, Xiao‑Wei Wang, Xiao‑Wu Chen, Zi‑Jing Kang, Xin Zhang, Rhonda R. Wilbur, Feng Cheng, Shu‑Feng Zhou
Oncology Letters 2013 5: 1813-1818 - Multi-gene molecular signatures for predicting the risk of atherosclerosis
Feng Cheng, Ellen C. Keeley, Klaus Ley, and Jae K. Lee
BMC Medical Genomics 2012 5:2 - Interaction Models of a Series of Oxadiazole-Substituted alpha-Isopropoxy Phenylpropanoic Acids Against PPAR alpha and PPAR gamma
Feng Cheng, Jianhua Shen, Xiaoying Xu, Xiaomin Luo, Kaixian Chen, Xu Shen and Hualiang Jiang
Protein and Peptide Letters 2009, 16, 150-162. - Molecular Docking Studies on the Interactions between the Thioesterase Domain of Human Fatty Acid Synthase and Its Ligands
Feng Cheng, Qinghua Wang, Florante A. Quiocho and Jianpeng Ma
PROTEINS: Structure, Function, and Bioinformatics 2008, 1228-1234. - A Solid State 13C NMR, Crystallographic and Quantum Chemical Investigation of Chemical Shifts and Hydrogen Bonding in Histidine Dipeptides
Feng Cheng, Haihong Sun Yong Zhang, Dushyant Mukkamala and Eric Oldfield
J. Am. Chem. Soc. 2005, 127(36): 12544-12554. - Inhibition of Isoprene Biosynthesis Pathway Enzymes by Phosphonates, Bisphosphonates, and Diphosphates
Feng Cheng and Eric Oldfield
J. Med. Chem. 2004, 47: 5149-5158. - Quantum Chemistry Study on the Interaction of the Exogenous Ligands and the Catalytic Zinc Ion in Matrix Metalloproteinases
Feng Cheng, Xiaomin Luo, Jianhua Shen, Xin Li, Jiande Gu, Weiliang Zhu, Ruihao Zhang, Jingkang Shen, Irit Sagi, Ruyun Ji, Kaixian Chen and Hualiang Jiang.
J. Phys. Chem. B, 2002, 106: 4552-4559 - Steered Molecular Dynamics Simulations on the Tail Helix Latch Hypothesis in the Gelsolin Activation Process
Feng Cheng, Jianhua Shen, Xiaomin Luo, Hualiang Jiang and Kaixian Chen.
Biophys. J. 2002, 83: 753-762. - Molecular Docking and 3D-QSAR Studies on the Possible Antimalarial Mechanism of Artemisinin Analogues
Feng Cheng, Jianhua Shen, Xiaomin Luo, Weiliang Zhu, Jiande Gu, Ruyun Ji, Hualiang Jiang and Kaixian Chen.
Bioorg. & Med. Chem. 2002, 10: 2883-2891. - The progress in the design of Matrix metalloproteinase
Feng Cheng, Hong Liu, Hualiang Jiang, Kaixian Chen and Ruyun Ji
Progress in Chemistry (Chinese), 2001, 13(4): 283-293 - The research progress of PPAR agonists
Feng Cheng, Jianhua Shen, Xiaomin Luo, Jingkang Shen, Hualiang Jiang and Kaixian Chen
Chin. Med. Chem.(Chinese) 2003, 13: 110-120. - Crystal Structure of Unliganded Influenza B Virus Hemagglutinin
Qinghua Wang, Feng Cheng, Mingyang Lu, Xia Tian, and Jianpeng Ma
Journal of Virology 2008, 82: 3011–3020 - Agonist-PPAR Interactions: A Molecular Modeling Study with Docking Approach
Xiaoying Xu, Feng Cheng, Jianhua Shen, Xiaomin Luo, Lili Chen, Liduo Yue, Yi Du, Fei Ye, Shanhao Jiang, Dayuan Zhu, Hualiang Jiang and Kaixian Chen.
Int. J. Quantum Chem. 2003, 93: 405-410. - Binding Mechanism of H5N1 Influenza Virus Neuraminidase with Ligands and its Implication for Drug Design
K. Gong, L. Li, J.-F. Wang, F. Cheng, D.-Q. Wei and K.-C. Chou
Medicinal Chemistry 2009, 5, 242-249 - Concordant gene expression signatures predict clinical outcomes of cancer patients undergoing chemotherapy
Paul D. Williams, Sooyoung Cheon, Dmytro M. Havaleshko, Hyeon Jeong, Feng Cheng, Dan Theodorescu and Jae K. Lee
Cancer Research 2009, 69 (21), 8302-8309 - Virtual Screening on Natural Products for Discovering Active Compounds and Target Information
Jianhua Shen, Xiaoying Xu, Feng Cheng, Hong Liu, Xiaomin Luo, Jingkang Shen, Kaixian Chen, Weimin Zhao, Xu Shen and Hualiang Jiang.
Curr. Med. Chem. 2003, 10, 1241-1253. - Structure-Based 3-D-QSAR Analysis of Marine Indole Alkaloids
Biao Jiang, Wen-Nan Xiong, Cai-Guang Yang, Hua-Liang Jiang, Feng Cheng, Kai-Xian Chen.
Bioorg. Med. Chem. 2002, Aug;10(8):2775-8. - Binding analyses between Human PPARgamma-LBD and ligands.
Changying Yu, Lili Chen, Haibing Luo, Jing Chen, Feng Cheng, Chunshan Gui, Ruihao Zhang, Jianhua Shen, Kaixian Chen, Hualiang Jiang and Xu Shen
Eur J Biochem, 2004, 271: 386-397. - Structure-Based Discovery of Potassium Channel Blockers from Natural Products: Virtual Screening and Electrophysiological Assay Testing
Hong Liu, Yang Li, Mingke Song, Xiaojian Tan, Feng Cheng, Suxin Zheng, Jianhua Shen, Xiaomin Luo, Ruyun Ji, Jianmin Yue, Guoyuan Hu, Hualiang Jiang, and Kaixian Chen
Chemistry & Biology, 2003, 10,1103-1113. - Differentiation of Cation-pi Bonding from Cation-pi Interactions: A Quantum Chemistry Study Using Density-Functional Theory and Morokuma Decomposition Methods.
Weiliang Zhu, Xiaojian Tan, Jianhua Shen, Xiaomin Luo, Feng Cheng, Puah Chum Mok, Ruyun Ji, Kaixian Chen, Hualiang Jiang.
J. Phys. Chem. A, 2003, 13: 2296-2303. - Steered Molecular Dynamics Simulation on the Binding of NNRTI to HIV-1 RT.
Lingling Shen, Jianhua Shen, Xiaomin Luo, Feng Cheng, Yechun Xu, Kaixian Chen, Edward Arnold, Jianping Ding, and Hualiang Jiang.
Biophysical Journal, 2003, 84:3547-3563. - Structure Feature of AChE Inhibitor Huperzine B in Nature and in the Binding Site of AChE: Density Functional Theory Study Combined with IR Determination
Xiaomin Luo, Feng Cheng, Xiaojian Tan, Dayuan Zhu, Kaixian Chen, Hualiang Jiang et al.
J. Theo. Comput. Chem. 2002, 1: 81-92. - Structural Characterization of the Catalytic Active Site in the Latent and Active Natural Gelatinase B from Human Neutrophils
Oded Kleifeld, Philippe E. Van den Steen, Anatoly Frenkeli, Feng Cheng, Hualiang Jiang, Ghislain Opdenakker, and Irit Sagi.
J. Biol. Chem. 2000, 275: 34335-34343.
Conference papers
- A Universal Computational Model for the Hepatotoxicity Evaluation in vivo and in vitro
Feng Cheng and Jae K. Lee
Poster and Abstract in 18th annual Growth Factor and Signal Transduction Symposium titled “Systems Biology: Integrative, Comparative, and Multi-Scale Modeling” in Ames, IOWA, 2009 - Molecular recognition of oxadiazole-substituted alpha-isopropoxy phenylpropanoic acids by PPAR-gamma and PPAR-alpha: Molecular modeling and 3D-QSAR studies
Feng Cheng and Hualiang Jiang
Poster and Abstract in 51st Biophysical Society Annual Meeting in Baltimore, Maryland
BIOPHYSICAL JOURNAL Pages: 387A-387A 2007. - Interleukin-6 and TNF Inhibit Insulin Uptake and Insulin-Induced Phosphorylation of Caveolin-1 in Bovine Aortic endothelial Cells
Hong Wang, Feng Cheng, Zhenqi Liu, Eugene J. Barrett
Abstract in American Diabetes Association conference in Chicago, Illinois 2007
Book Chapters
- Chapter: “Multivariate molecular expression-based predictions of clinical outcome”
Feng Cheng, Sang-Hoon Cho, and Jae K. Lee.
Book: “Statistical Methods in Molecular Biology”. Human Press, 2010